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# Magnesium Sulfate
## Overview
Magnesium sulfate is an essential mineral that plays a crucial role in numerous biochemical reactions. It is available for intravenous (IV) and intramuscular (IM) administration.
## Primary Indications
* **Eclampsia/Preeclampsia:** Prevention and treatment of seizures in patients with severe preeclampsia or eclampsia.
* **Torsades de Pointes:** Treatment of polymorphic ventricular tachycardia (Torsades de Pointes) associated with a prolonged QT interval.
* **Hypomagnesemia:** Treatment of magnesium deficiency.
* **Bronchodilator (Adjunctive):** Adjunctive treatment for severe asthma exacerbations refractory to standard therapy.
## Adult Dosing
* **Eclampsia/Preeclampsia:**
* **Loading Dose:** 4-6 grams IV infused over 5-20 minutes.
* **Maintenance Dose:** 1-2 grams/hour IV infusion. Dosing may be adjusted based on clinical response and magnesium levels. Some protocols may use IM dosing (e.g., 5 grams IM into each buttock every 4 hours if IV access