Liquid%2525252525252525252525252525252525252525252525252525252525252525252520paraffin

# Liquid Paraffin ## Overview Liquid paraffin is a mineral oil used as an emollient and laxative. It works by lubricating the intestinal tract, softening the stool and making it easier to pass. ## Primary Indications * Constipation ## Adult Dosing * **Laxative:** 10-30 mL once daily, typically at bedtime. * **Emollient:** Applied topically as needed. ## Pediatric Dosing * **Constipation (Age 1-12 years):** 5-10 mL once daily, typically at bedtime. Dosing should be guided by clinical response and local protocol. Maximum daily dose generally not to exceed 20 mL. * **Infants (under 1 year):** Generally not recommended due to increased risk of aspiration. Consult specialist if considered. ## Dose Adjustments No specific dose adjustments are required for renal or hepatic impairment. ## Contraindications * Appendicitis or symptoms of acute abdominal conditions. * Intestinal obstruction. * Hypersensitivity to liquid paraffin. * Children under 1 year old (oral use due to risk of aspiration). ## Adverse Effects * Anal leakage, abdominal cramping, diarrhea, nausea, vomiting, and perianal irritation. * Long-term use may lead to vitamin malabsorption (fat-soluble vitamins A, D, E, K). * Risk of lipoid pneumonia if aspirated. ## Key Drug Interactions * Concurrent use with other mineral oil products can increase laxative effect and risk of adverse events. * May reduce absorption of fat-soluble vitamins and other orally administered medications. Separate administration by at least 2 hours. ## Monitoring * Monitor for bowel movements and stool consistency. * Assess for signs of abdominal discomfort or leakage. * Consider monitoring for fat-soluble vitamin deficiencies with long-term use. ## Clinical Pearls * Administer at bedtime to minimize daytime discomfort. * Avoid use in patients with dysphagia or an impaired gag reflex due to aspiration risk. * Do not administer within 2 hours of other medications. * For topical use, apply sparingly to affected areas. *** *Disclaimer: This information is intended for healthcare professionals. Always consult the most current prescribing information and institutional guidelines before making clinical decisions.*