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# IV Dexamethasone ## Overview Dexamethasone is a potent synthetic glucocorticoid with anti-inflammatory and immunosuppressive properties. It is available as a sodium phosphate salt (water-soluble) or acetate salt (less soluble). ## Primary Indications * Allergic states * Dermatologic conditions * Endocrine disorders * Gastrointestinal diseases * Hematologic disorders * Neoplastic conditions (e.g., palliative care, treatment of cerebral edema) * Nervous system conditions * Ophthalmic diseases * Renal diseases * Respiratory diseases * Rheumatic disorders * Treatment of COVID-19 in hypoxic patients ## Adult Dosing Dosing is highly variable and depends on the specific indication and severity of the condition. A common starting dose range is 0.5 mg to 9 mg per day, divided