Iron%252525252525252525252525252525252525252525252525252520sucrose

# Iron Sucrose ## Overview Iron sucrose is an intravenous iron preparation used to treat iron deficiency anemia. It replaces iron stores and allows for the production of hemoglobin. ## Primary Indications * Iron deficiency anemia (IDA) in patients who are unable to tolerate or fail oral iron therapy. * IDA in patients with chronic kidney disease (CKD), including those on hemodialysis and non-dialysis. ## Adult Dosing Dosage is highly individualized based on the degree of iron deficiency and patient weight. Total dose required is often calculated using formulas. * **Repletion Dose (Total Calculated Dose):** Typically ranges from 1000 mg to 2000 mg per treatment course. * **Dosing Regimen:** * Administered in multiple doses. A common regimen is 15 mL (750 mg) of iron sucrose (typically supplied as 100 mg/5 mL vials) administered intravenously over at least 10-15 minutes once or twice weekly until the total calculated dose is reached. * Alternatively, a single infusion of 1000 mg (20 mL) may be given over at least 10 minutes, repeated as necessary to reach the total dose. * **Maximum Single Infusion Dose:** 125 mg elemental iron (2.5 mL of a 100 mg/5 mL solution) for patients undergoing hemodialysis. For non-dialysis patients, single doses up to 1000 mg (20 mL) can be administered. * **Maximum Cumulative Dose:** Up to 1000 mg elemental iron per dose for non-dialysis patients; up to 125 mg elemental iron for hemodialysis patients. The total iron required depends on the desired hemoglobin level and body weight. ## Pediatric Dosing Dosing needs to be calculated based on weight and severity of anemia. Specific protocols may vary. * **Repletion Dose:** Calculated based on weight: * Children < 15 kg: 15 mg/kg of elemental iron. * Children ≥ 15 kg: 1000 mg of elemental iron. * **Dosing Regimen:** Administered in divided