Please check your internet connection and try again.
# Ferrous Ascorbate
## Overview
Ferrous ascorbate is an iron supplement used to treat iron deficiency anemia. The ascorbic acid component enhances iron absorption.
## Primary Indications
Treatment and prevention of iron deficiency anemia.
## Adult Dosing
* **Iron deficiency anemia:** Typically 100 mg to 200 mg elemental iron daily, divided into 1 to 2 doses. A common prescription is 60 mg elemental iron (equivalent to 300 mg ferrous ascorbate) BID.
* **Prophylaxis:** May be lower, as directed by prescriber.
## Pediatric Dosing
* **Iron deficiency anemia:** Dosing varies significantly by age and weight. Recommended elemental iron intake is typically 3 mg/kg/day, divided BID. A common starting dose is 15 mg elemental iron (equivalent to 75 mg ferrous ascorbate) BID in infants and children. Maximum daily elemental iron dose is usually 65 mg.
* **Prophylaxis:** Lower doses as directed by prescriber.
_Exact pediatric dosing should be guided by current pediatric hematology guidelines or prescriber specific protocols._
## Dose Adjustments
No dose adjustments are typically required for renal or hepatic impairment, though caution is advised.
## Contraindications
* Known hypersensitivity to ferrous ascorbate or its components.
* Patients with hemochromatosis or other causes of iron overload.
* Untreated vitamin B12 deficiency (can mask signs/symptoms).
* Use with frequent blood transfusions.
## Adverse Effects
* **Gastrointestinal:** Nausea, vomiting, constipation, diarrhea, abdominal pain, dark stools (expected).
* **Other:** Skin rash, allergic reactions.
## Key Drug Interactions
* **Antacids, calcium supplements, tetracyclines, fluoroquinolones, levothyroxine, penicillamine, bisphosphonates:** Can decrease iron absorption. Separate administration by at least 2 hours.
* **Vitamin E:** May reduce iron absorption.
## Monitoring
* Hemoglobin and hematocrit.
* Iron studies (serum ferritin, transferrin saturation) may be monitored periodically.
* Signs and symptoms of anemia resolution.
* Monitor for gastrointestinal side effects.
## Clinical Pearls
* Administer on an empty stomach to maximize absorption, but if gastrointestinal upset occurs, take with food (avoiding interactions).
* Concurrent vitamin C intake enhances iron absorption.
* Stool darkening is an expected and benign side effect.
* Iron poisoning is a serious risk in children; store out of reach.
***
**Disclaimer:** This information is for educational purposes only and does not substitute for professional medical advice. Always consult with a qualified healthcare provider to ensure the most accurate and up-to-date information for your specific situation. Verify current prescribing information before making any treatment decisions.
