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# Ezivac enema
## Overview
Ezivac enema is a hyperosmotic laxative used for bowel preparation and management of occasional constipation. It works by drawing water into the colon, softening stool and stimulating bowel movement.
## Primary Indications
* Bowel preparation prior to colonoscopy or surgery.
* Relief of occasional constipation.
## Adult Dosing
* **Bowel preparation:** Typically, one 133 mL enema administered rectally 1-6 hours before the procedure. Follow specific institutional or procedural guidelines for timing and additional bowel prep agents.
* **Constipation:** One 133 mL enema administered rectally as a single dose.
## Pediatric Dosing
Safety and efficacy in pediatric patients have not been established. Use in pediatric patients generally not recommended without specific medical guidance; if used, dosing and administration should be individualized and carefully supervised by a healthcare professional.
## Dose Adjustments
No dose adjustments are typically required for hepatic or renal impairment.
## Contraindications
* Gastrointestinal obstruction.
* Appendicitis, appendicitis symptoms.
* Intestinal perforation.
* Congenital or acquired megacolon/microcolon.
* Known hypersensitivity to the active ingredient or any component of the enema.
* Use with caution in patients with impaired gag reflex, regurgitation, or decreased consciousness due to risk of aspiration.
## Adverse Effects
* Abdominal discomfort, cramping, bloating.
* Nausea, vomiting.
* Diarrhea.
* Rect