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# Azithromycin
## Overview
Azithromycin is a macrolide antibiotic effective against a broad spectrum of bacteria. It inhibits bacterial protein synthesis by binding to the 50S ribosomal subunit.
## Primary Indications
* **Respiratory Tract Infections:** Community-acquired pneumonia, acute exacerbations of chronic bronchitis, pharyngitis/tonsillitis (Streptococcus pyogenes).
* **Skin and Soft Tissue Infections:** Uncomplicated skin and skin structure infections.
* **Sexually Transmitted Infections:** Chlamydia trachomatis, Neisseria gonorrhoeae (uncomplicated urogenital infections).
* **Mycobacterium avium complex (MAC) prophylaxis and treatment** in patients with advanced HIV infection.
* **Otitis Media:** Acute bacterial otitis media.
## Adult Dosing
* **Community-Acquired Pneumonia:** 500 mg on day 1, followed by 250 mg once daily on days 2-5.
* **Acute Bacterial Exacerbations of Chronic Bronchitis:** 500 mg on day 1, followed by 250 mg once daily on days 2-5.
* **Pharyngitis/Tonsillitis:** 500 mg on day 1, followed by 250 mg once daily on days 2-5 OR a single 500 mg dose.
* **Chlamydia trachomatis (uncomplicated urogenital):** Single oral dose of 1 gram.
* **Neisseria gonorrhoeae (uncomplicated
