Azitgro%252525252525252520%252525252525252528azithromycin%252525252525252529

# Azithromycin ## Overview Azithromycin is a macrolide antibiotic. It works by inhibiting bacterial protein synthesis. ## Primary Indications * **Community-acquired pneumonia (CAP):** Typically used for atypical pathogens or as part of a multidrug regimen for typical pathogens. * **Acute exacerbations of chronic bronchitis (AECB):** In patients with underlying lung disease. * **Streptococcal pharyngitis:** As an alternative to penicillin in patients with penicillin allergy. * **Uncomplicated skin and skin structure infections:** Generally caused by susceptible Gram-positive organisms. * **Genital ulcer disease:** Chancroid. * **Chlamydia trachomatis infections:** Urethritis and cervicitis. * **Disseminated Mycobacterium avium complex (MAC) disease:** Prophylaxis and treatment in HIV-infected individuals. ## Adult Dosing * **CAP:** 500 mg on day 1, followed by 250 mg once daily on days 2-5. Alternatively, a single 1g dose. * **AECB:** 500 mg on day 1, followed by 250 mg once daily on days 2-5. * **Streptococcal pharyngitis:** A single 500 mg dose or 250 mg twice daily for 10 days. * **Uncomplicated skin infections:** 500 mg on day 1, followed by 250 mg once daily on days 2-5. * **Chancroid:** Single dose of 1 g. * **Chlamydia trachomatis infections:** Single dose of 1 g. * **MAC prophylaxis (HIV):** 1.2 g once weekly. * **MAC treatment (HIV):** 500-600 mg twice daily in combination with other agents. Dosing often depends on specific guidelines and clinical response. ## Pediatric Dosing Dosing varies significantly by indication and age/weight. Exact dosing should be confirmed with current pediatric guidelines or product information. * **CAP (3 months to 5 years):** 10 mg/kg on day 1, followed by